Table 3.

Mixed-effects model summary to predict worst pain in the subset after 120 days.

Effect	Estimate	P
Intercept	9.11	<0.0001
Age (per year)	−0.009	0.35
Gender
Female	Ref
Male	+0.42	0.12
Drug
Morphine	Ref
Methadone	−0.31	0.32
Pain classification
Nociceptive	Ref
Neuropathic	−0.84	0.02
Mixed	−0.46	0.16
Nociplastic	+1.04	0.03
Missing data	−2.45	0.19
Random effects (time, id*)	—	0.07

^*id: subject. Generalized additive model with integrated smoothness estimation.