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. 2021 Dec 13;2021:5048375. doi: 10.1155/2021/5048375

Figure 4.

Figure 4

Effects of SeMet and Tau alone or in combination on the inflammation and blood-milk barrier in the presence of LPS in BMECs. (a, b) The mRNA levels of pro-inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8. (c) The levels of inflammatory mediators NO, iNOS, and COX-2. (d) The mRNA levels of tight junction proteins ZO-1, Occludin, and Claudin1. All results are presented as the means ± SEM (n = 3). Significance compared with control, ∗P < 0.05 and ∗∗P < 0.01. Within the LPS-treated groups, significance compared with LPS group, #P < 0.05, ##P < 0.01, &P < 0.05, and &&P < 0.01.