Figure 2.

Sorafenib sensitivity after plasmid transfection. Relative cell viability under different doses of sorafenib treatment for 24 h and comparison of IC₅₀ value of sorafenib treatment for 24 h among groups in Huh7 and Hep3B cells after transfection (A). Relative cell viability under different doses of sorafenib treatment for 72 h and comparison of IC₅₀ of sorafenib treatment for 72 h among groups in Huh7 and Hep3B cells after transfection (B). SENP2, Small ubiquitin-like modifier specific peptidase 2; NC, negative control; IC₅₀, half maximal inhibitory concentration.