Table 2:

Acute grade ≥ 2 and grade ≥ 3 toxicity. Data presented as n (% of the total N for the relevant treatment group).

	PHASE III			PHASE II/III
	IMRT (n=13)	PET-BMS-IMRT (n=16)	P	IMRT (n=55)	PET-BMS-IMRT (n=46)	P
TOXICITY
Neutropenia
Grade ≥ 2	9 (69%)	8 (50%)	0.30	31 (56%)	22 (48%)	0.39
Grade ≥ 3	7 (54%)	3 (19%)	0.048*	19 (35%)	6 (13%)	0.01*
Lymphopenia
Grade ≥ 2	4 (31%)	5 (31%)	0.98	17 (31%)	16 (35%)	0.68
Grade ≥ 3	1 (8%)	1 (6%)	0.88	6 (11%)	4 (9%)	0.75
Thrombocytopenia
Grade ≥ 2	1 (8%)	2 (13%)	0.36	6 (11%)	7 (15%)	0.56
Grade ≥ 3	0 (0%)	1 (6%)	0.67	4 (7%)	1 (2%)	0.37
Anemia
Grade ≥ 2	6 (46%)	10 (63%)	0.38	23 (42%)	21 (46%)	0.70
Grade ≥ 3	1 (8%)	3 (19%)	0.39	1 (2%)	3 (7%)	0.33
Leukopenia
Grade ≥ 2	8 (62%)	12 (75%)	0.44	41 (75%)	31 (67%)	0.43
Grade ≥ 3	5 (38%)	7 (44%)	0.77	21 (38%)	14 (30%)	0.42
Any Hematologic Toxicity
Grade ≥ 2	10 (77%)	14 (88%)	0.45	47 (85%)	38 (83%)	0.70
Grade ≥ 3	7 (54%)	9 (56%)	0.90	25 (45%)	17 (37%)	0.39
Gastrointestinal Toxicity
Grade ≥ 2	3 (23%)	2 (13%)	0.44	17 (31%)	17 (37%)	0.51
Grade ≥ 3	0 (0%)	0 (0%)	-	1 (2%)	2 (4%)	0.59

^*Variable was unbalanced (P<.05) between groups.