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. 2021 Dec 7;11:809410. doi: 10.3389/fonc.2021.809410

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Copyright © 2021 Huang, Zhang, Dong, Chen, Shao and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lower MiR-98 Levels are Correlated with Worse Prognosis in EC. (A) Schematic representation of the predicted binding between MRP-7 3′-UTR sequence and miR-98 (TargetScan database). (B) The expression of miR-98 in EC and normal tissues were examined using qRT-PCR assays. (C–E) MiR-98 levels were significantly decreased in EC patients with advanced tumors (C), late-stage disease (D), or deeper myometrial invasion (E). (F) EC cells have a much lower expression of miR-98 than normal HESC cells. (G) The relationship between miR-98 expression and the overall survival of EC patients (KM plotter database). ***P < 0.001.