Table 1.
Cohort Characteristics by Liver Disease Status
| Characteristic | AIH n=935 | Other CLD n=120,100 | No CLD n= 18,474,310 | AIH vs Other CLD p-value | AIH vs no CLD p-value |
|---|---|---|---|---|---|
| Age, mean (SE), years | 29.6 (0.41) | 29.5 (0.04) | 28.5 (0.003) | 0.85 | 0.01 |
|
| |||||
| Race/ethnicity, n (%)*: | |||||
| White | 445 (52.4) | 63,705 (56.8) | 9,265,357 (53.6) | <.001 | 0.07 |
| Black | 165 (19.4) | 12,600 (11.2) | 2,504,540 (14.5) | ||
| Hispanic | 125 (14.7) | 9,630 (8.6) | 3,561,334 (20.6) | ||
| Asian/Pacific Islander | 40 (4.7) | 20,400 (18.2) | 998,960 (5.8) | ||
| Other | 75 (8.8) | 5,905 (5.2) | 951,780 (5.5) | ||
|
| |||||
| Urban or rural-based hospital, n (%)**: | |||||
| Rural | 120 (12.8) | 19,470 (16.2) | 2,558,577 (13.9) | 0.21 | 0.67 |
| Urban | 815 (87.2) | 100,385 (83.8) | 15,842,542 (86.1) | ||
|
| |||||
| Multiple gestation, n (%) | 0 (0) | 2,315 (2.0) | 327,935 (1.8) | 0.06 | 0.07 |
|
| |||||
| Diabetes, n (%) | 20 (2.1) | 2,215 (1.8) | 202,300 (1.1) | 0.77 | 0.17 |
|
| |||||
| Obesity, n (%) | 105 (11.2) | 9,435 (7.9) | 1,336,240 (7.2) | 0.09 | 0.03 |
|
| |||||
| Dyslipidemia, n (%) | ≤10 (1.1)*** | 665 (0.6) | 33,335 (0.2) | 0.97 | 0.25 |
|
| |||||
| Hypertension, n (%) | 100 (10.7) | 5,360 (4.5) | 565,550 (3.1) | <.001 | <.001 |
|
| |||||
| Cirrhosis, n (%) | 60 (6.4) | 845 (0.7) | ----- | <.001 | ----- |
Abbreviations: autoimmune hepatitis (AIH), chronic liver disease (CLD);
*
missing in n=290 AIH (5.1%), 7,640 other CLD (6.7%), and n=1,170,125 other CLD (6.3%);
**
missing in n=10 AIH (0.2), 230 other CLD (0.2%), and n=50,895 other CLD (0.3%);
***
Indicates ≤ 10 outcomes, thus exact estimates not permitted for reporting due to Healthcare Cost and Utilization Project regulations.