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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Head Neck. 2021 Oct 25;44(1):177–188. doi: 10.1002/hed.26906

Figure 4. Genes with greater expression in cervical cancers also increased in HNSCCs compared to adjacent normal solid tissues.

Figure 4.

A. mRNA expression of LCE1B, KRT16, SPRR2G and FBN2 in primary tumors of HNSCC (n=520) compared to adjacent normal solid tissue (n=44). B. Quantitative PCR analysis of LCE1B, KRT16, SPRR2G and FBN2 in HPV negative and positive HNSCC cell lines. Differential gene expression between HPV negative and positive HNSCC cell lines were determined and was normalized to GAPDH (LCE1B, SPRR2G, FBN2) or 36B4 (KRT16) as an internal control. C. Western blot analysis of KRT16 and FBN2 in HPV negative and positive HNSCC cell lines. Two isoforms of FBN2 (300kDa and 160kDa) were detected. GAPDH was used as a loading control. ImageJ analysis, normalized to GAPDH, of KRT16 and the two isoforms of FBN2 is shown.