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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Invest Dermatol. 2021 Aug 5;142(1):155–165.e3. doi: 10.1016/j.jid.2021.05.029

Figure 2. IFN-κ regulates IMQ-induced ear thickness and splenomegaly.

Figure 2.

(a) Ifnk expression and (b) body weight after 8 days of IMQ or vehicle treatment. (c) Representative photographs of ears from treated and untreated male and female mice. (d) Change in ear thickness was assessed. n = 12‒20 mice per group. * P < 0.05, ** P < 0.01, **** P < 0.0001. (e) Representative images of spleens from IMQ-treated and control mice. (f) Spleen weight quantitation. n = 12‒20 mice per group. Statistical significance levels are indicated as *** P < 0.001 and **** P < 0.0001. IMQ, imiquimod; KO, knockout; TG, transgenic; Tx, treatment; WT, wild type.