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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Invest Dermatol. 2021 Aug 5;142(1):155–165.e3. doi: 10.1016/j.jid.2021.05.029

Figure 3. IFN-κ acts as a rheostat for IMQ-mediated psoriatic changes.

Figure 3.

(a) Representative H&E-stained ear sections of untreated and IMQ-treated male and female mice. (b‒e) Scoring of inflammation for each indicated metric was conducted in a blinded fashion by a dermatopathologist. (f) Average of acanthosis (in μm) across the entire ear section. Images are representative of sections from 12‒20 mice per group examined. Bar = 50 μm. *P < 0.05; ** P < 0.01; ***P < 0.001; **** P < 0.0001. IMQ, imiquimod; KO, knockout; TG, transgenic; Tx, treatment; WT, wild type.