Table 2.
Clinical and laboratory characteristics of patients according to their ICU-AW status at day 10 of their critical illness; p-values that indicate significant differences are printed in bold.
| CINM− | CINM+ | p-value | |
|---|---|---|---|
| Patient no. | 18 | 25 | |
| mean age (years ± SD) | 67.89 ± 14.7 | 66.6 ± 13.82 | 0.770 |
| sex (% male) | 0.72 | 0.64 | 0.570 |
| mean APACHE II ± SD | 25.11 ± 4.78 | 25.72 ± 6.13 | 0.727 |
| SOFA ± SD day 3 | 10.28 ± 2.49 | 13.12 ± 2.86 | 0.002 |
| SOFA ± SD day 10 | 4 ± 3.88 | 7.63 ± 4.13 | 0.006 |
| % diabetes* | 56 | 84 | 0.041 |
| pH | 7.42 ± 0.05 | 7.42 ± 0.07 | 0.854 |
| K+ (mM) | 4.31 ± 0.5 | 4.5 ± 0.45 | 0.199 |
| Na+ (mM) | 143.33 ± 3.68 | 144.16 ± 4.35 | 0.516 |
| Ca2+ (mM) | 1.16 ± 0.06 | 1.14 ± 0.07 | 0.596 |
| Glucose (mM) | 6.92 ± 1.3 | 7.64 ± 1.86 | 0.164 |
| CRP (mg/l) | 214.94 ± 143.32 | 231.42 ± 116.65 | 0.691 |
| PCT (ng/ml) | 5.02 ± 8.96 | 11.79 ± 21.13 | 0.209 |
| Healthy controls | Patients day 3 | ||
|---|---|---|---|
| CMAP ADM (mV) | 13.3 ± 2.3 | 4.9 ± 2.2 | < 0.0001 |
| CMAP EDB (mV) | 6.1 ± 2 | 1.6 ± 1.5 | < 0.0001 |
| SNAP radial nerve (µV) | 41.7 ± 13.1 | 12.7 ± 6.6 | < 0.0001 |
| SNAP sural nerve (µV) | 16.2 ± 4.3 | 11.8 ± 5.5 | 0.04 |
| Healthy controls | Patients day 10 | ||
|---|---|---|---|
| CMAP ADM (mV) | 13.3 ± 2.3 | 5.5 ± 2.9 | < 0.0001 |
| CMAP EDB (mV) | 6.1 ± 2 | 1.2 ± 1.3 | < 0.0001 |
| SNAP radial nerve (µV) | 41.7 ± 13.1 | 14.2 ± 6.2 | < 0.0001 |
| SNAP sural nerve (µV) | 16.2 ± 4.3 | 8.8 ± 5.1 | < 0.001 |
Demographic and clinical parameters except for the SOFA-score refer to the day of admission, laboratory parameters refer to day 3. For numerical data, p-values were calculated using t-tests for independent samples. For categorical data, χ2 tests were used.
*Only patients without manifest diabetic polyneuropathy were included in this study.