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. 2021 Dec 20;11:24285. doi: 10.1038/s41598-021-03346-0

Table 3.

Demographic characteristics for placebo and treated patients of the subset.

Characteristics Placebo + MTX (n = 11) Tocilizumab 8 mg/kg (n = 23) p value
Age 53.4 (20–72) 54.9 (20 – 76) 0.779
Gender, % female 81.8% 95.5% 0.252
Ethnicity

72.7% Non-Hispanic

27.3% Hispanic

90.9% Non-Hispanic

9.1% Hispanic

0.304
Race 100% White

95.5% White

4.5% Other

0.999
CRP 4.339 (0.581–24.100) 2.623 (0.113–12.500) 0.299
ESR 51.73 (17–186) 45.64 (8–118) 0.780
HAQ 1.750 (0.375–3.000) 1.517 (0.375–2.750) 0.274
SJC 18.09 (7–39) 18.14 (7–36) 0.858
TJC 28.18 (9–46) 31.73 (8–66) 0.456
VAS PAIN 58.72 (29–79) 63 (21–98) 0.645
DAS 6.649 (4.441–7.702) 6.804 (5.458–8.668) 0.873

Categorical variables are described as percentages, while continuous variables as means (range) and were compared between the two groups (placebo and treated) with Mann–Whitney test. P values are shown in the last column. Statistical significance is considered as *P < 0.05, ns = P > 0.05. CRP: C-reactive protein, ESR: erythrocyte sedimentation rate, HAQ: health assessment questionnaire, SJC: swollen joint count, TJC: tender joint count, VAS: visual analogue scale, DAS: disease activity score.