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. 2021 Dec 20;13(1):12. doi: 10.1038/s41419-021-04464-3

Fig. 2. miR-541-5p was regulated by circMTO1.

Fig. 2

A The intersected miRNAs were predicted from the four databases. B ENCORI database-predicted sites through which miRNAs bind to circMTO1. C, D Pull-down assays were performed using circMTO1 probes in HepG2 and SMMC-7721 cells, and circMTO1, linear MTO1, and miRNAs enrichment was detected using RT-qPCR. E HEK293T cells were co-transfected with miR-541-5p mimics and Wt or Mut circMTO1 luciferase reporter vectors, and luciferase reporter activity was detected. Data were presented as mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.