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. 2021 Dec 20;7:89. doi: 10.1038/s41522-021-00261-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Bar chart displaying number of samples within each dominant species group. Box plots show relative abundance of species and Shannon diversity index of each dominant species group with bounds of the box representing the first and third quartiles, the center line representing the median and whiskers as min-to-max values. b Microbiome profiles of women with outcome data classified by vaginal microbiome groups (VMG). Color of species denotes the VMG group classification with VMG I (L. crispatus dominated, blue), II (L. gasseri dominated, green), III (L. iners dominated, orange), IV-A (bacterial vaginosis associated, red), IV-B (non-BV taxa, pink), V (L. jensenii dominated, purple), VI (Other Lactobacillus, light blue), and VII (Bifidobacterium dominated, light purple). c Correlation plot for dominant species showing correlation strength (circles), relationship (positive, blue; negative, red) and significance (***, p < 0.001; **, p < 0.01; *, p < 0.05).