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. 2021 Dec 20;11:24224. doi: 10.1038/s41598-021-03632-x

Table 1.

Clinical symptoms and signs according to disease severity (N = 312).

Symptom or sign Disease severity
Non-severe (%) (N = 208) Severe (%) (N = 104)
Altered level of consciousness 1 11
Fever (≥ 37.5 °C) 65 89
Cough 44 52
Sputum 16 24
Sore throat 19 13
Nasal discharge 14 1
Dysgeusia 22 13
Dysosmia 18 9
Shortness of breath 14 50
Diarrhea 10 16
Nausea and vomiting 2 9
Malaise 27 52
Bacterial infection 2 27
Fungal infection 0 5
Heart failure 0 13
Thromboembolism (including pulmonary embolism and cerebral infarction) 0 10
Liver dysfunction 4 39
Renal dysfunction 0 17
Macrophage activation syndrome (including hemophagocytic syndrome) 0 2