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. 2021 Dec 20;12:7342. doi: 10.1038/s41467-021-26280-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Forest plots showing the discovery-phase results for the 15 replicated genes. The centre of the error bars represents the PD odds ratio per 1-standard-deviation increase in gene expression, calculated using the Wald ratio (if 1 SNP) or IVW (if >1 SNP) and corrected for the number of genes tested. Results are colour-coded according to the tissue (red = blood, blue = brain tissue). 95% CI 95% confidence interval, FDR false discovery rate, OR odds ratio, PD Parkinson’s disease.