Table 3.
Univariate and multivariate analysis of overall survival in CRC.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Gender (male vs female) | 1.20 (0.64–2.30) | 0.550 | ||
| Age (≤60 years vs >60 years) | 1.90 (0.95–3.80) | 0.071 | ||
| Tumor diameter (≤5 cm vs >5 cm) | 1.30 (0.65–2.80) | 0.440 | ||
| Differentiation (well/moderate vs poor) | 1.90 (0.94–3.80) | 0.075 | ||
| TNM stage (I–II vs III–IV) | 4.60 (2.30–9.30) | <0.001a | 0.67 (0.18–2.51) | 0.550 |
| T stage (T1–T2 vs T3–T4) | 1.30 (0.46–3.70) | 0.620 | ||
| N stage (N0 vs N1–N2) | 4.30 (2.20–8.50) | <0.001a | 4.10 (1.30–13.00) | 0.015a |
| M stage (M0 vs M1) | 6.20 (3.10–12.0) | <0.001a | 5.90 (2.50–14.00) | <0.001a |
| UBQLN4 expression (negative vs positive) | 4.50 (1.60–13.0) | 0.005a | 3.40 (1.20–9.70) | 0.024a |
CRC colorectal cancer, HR hazard ratio, CI confidence interval.
aStatistical significance.