Fig. 7.

Signalling pathways

Schematic presentation of signalling pathways in human adipocytes (left) and muscle cells (right) affected by GH and predominantly based on the present findings. Arrows indicate activation and truncated lines indicate inhibition. GH-induced upregulation/activation is shown in green and downregulation/inactivation in red. Unaltered regulation/activation is shown in grey.

‘P’ indicates phosphorylation. AC: adenyl cyclase, ATP: adenosenine triphosphate, DAG: diacylglycerol, MAG: monoacylglycerol, MGL: monoglyceride lipase, VLDL: very-low-density lipoproteins.

For further details, see the result and discussion sections of the manuscript.