FIG. 6.

The C-terminal region of TAP is essential for export activity. Plasmids expressing the indicated portions of TAP (Fig. 5) fused to RevM10 were transfected into 293T cells and tested for activity as described in the legend to Fig. 1. A plasmid expressing NXT1 was cotransfected as indicated. Plasmids expressing Rev or RevM10 were also tested as controls. The values shown are averages of duplicate SEAP-normalized p24 levels.