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. 2021 Dec 7;8:761727. doi: 10.3389/fnut.2021.761727

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Copyright © 2021 Li, Suo, Huang, Dai, Bian, Zhu, Lin and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of WGQK on the abundance of five key gut bacteria (genus-level). (A) Heat map of the significant differential genera in the HFD and WGQK mice groups; (B) LEfSe analysis (Kruskal-Wallis < 0.01 Wilcoxon test < 0.01, LDA score > 3) of HFD vs. HFD+QK (for a clearer display of the key bacteria, only show genus and phylum-level enrichment in the HDF+QK group); (C–H) The relative abundance of six key genera enriched by WGQK, (C) Akkermansia; (D) Bifidobacterium; (E) Eubacterium__coprostanoligenes; (F) Lactobacillus Peptococcaceae_unclassified; (G) Candidatus_Saccharimonas; (H) Eubacterium__coprostanoligenes. Data are presented as mean ± SD (n = 5), significant difference was determined using an unpaired two-tailed t-test, different superscript letters of any two means represent significant differences (p < 0.05).