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. 2021 Oct 23;13(2):517–540. doi: 10.1016/j.jcmgh.2021.10.008

Table 1.

Characteristics of PDTOs Used for Chemotolerance Modeling in This Study

PDTO line Site of origin KRAS/NRAS/ BRAF PIK3CA APC TP53 SMAD2/3/4 MSI/MSS Histology grade
PDTO1 Primary tumor (liver metastatic) Wt Wt Mut Mut Wt MSS 2
PDTO2 Liver metastasis Wt Wt Mut Mut Wt MSS 2
PDTO5 Liver metastasis Wt Wt Mut Mut Wt MSS 2

Wt, wild-type; Mut, mutant; MSS, microsatellite stable.