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. 2021 Dec 2;3(1):100194. doi: 10.1016/j.xinn.2021.100194

Figure 2.

Figure 2

Correlation between stimulatory and inhibitory features in TCGA primary tumors

(A) The proportion of cancer types with positive (Rs > 0.2 and FDR < 0.05 in red) or negative (Rs < −0.2 and FDR < 0.05 in blue) correlation for expression of pairwise stimulatory (red) and inhibitory (blue) checkpoints in 33 cancer types.

(B) The Spearman's correlation of cytotoxic activity and the expression of checkpoints in cancers.

(C) The proportion of cancer types with positive correlation (Rs > 0.2 and FDR < 0.05 in orange) or negative correlation (Rs < −0.2 and FDR < 0.05 in purple) for relative abundance (GSVA scores) of the 28 immune cells in 33 cancer types.

(D) The Spearman's correlation of cytotoxic activity and relative abundance of immune cell populations in cancer. The sample size is listed in Table S2.