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. 2021 Dec 7;12:743890. doi: 10.3389/fimmu.2021.743890

Figure 3.

Figure 3

Imiquimod treatment modifies the proteome of human bronchial epithelial cells (HBECs) from patients with asthma. (A) Volcano plot showing differentially expressed proteins between imiquimod treated and control unstimulated HBECs from patients with steroid-free asthma (N = 3). Proteins down-regulated (blue dots; log2 fold-change < -1.5, p < 0.05) and up-regulated (red dots; log2 fold-change > 1.5, p < 0.05) are depicted. (B) STRING interaction network of the proteins down-regulated by imiquimod treatment. Only proteins interacting with high confidence score (0.700) are shown. Colors represent the most relevant enriched Reactome pathways.