Table 1.
Characteristics of the patient.
| Characteristics | Patients with PAH (n = 56) | ||
|---|---|---|---|
| Baseline | Follow-up | p value | |
| Male/female, n/n | 21/35 | ||
| Age, years | 62 ± 15 | ||
| PAH subtype, n (%) | |||
| Idiopathic PAH | 55 (98.2) | ||
| PAH with overt features of venous/capillary involvement | 1 (1.8) | ||
| WHO FC, n (%) | |||
| I | 4 (7.1) | <0.001 | |
| II | 11 (19.6) | 16 (28.6) | |
| III | 40 (71.4) | 29 (51.8) | |
| IV | 5 (8.9) | 7 (12.5) | |
| BNP (pg/ml) | 133 [65–307]* | 89 [29–249]* | 0.003 |
| Right heart catheterization | † | ||
| Mean pulmonary arterial pressure, mm Hg | 42 ± 10 | 40 ± 10 | 0.003 |
| Right atrial pressure, mm Hg | 8 [6–10] | 8 [6–11] | 0.127 |
| Pulmonary vascular resistance, Wood Units | 7.6 ± 3.1 | 6.0 ± 3.0 | 0.066 |
| Cardiac index, l/min/m2 | 2.4 ± 0.5 | 2.8 ± 0.7 | 0.147 |
| Pulmonary arterial wedge pressure, mm Hg | 11 [8–13] | 10 [9–13] | 0.547 |
| Pulmonary arterial capacitance, ml/mm Hg | 1.5 [1.0–2.0] | 1.7 [1.2–2.7] | 0.003 |
| Maximal treatment, n (%) | |||
| Monotherapy | 19 (33.9) | ||
| Dual therapy | 25 (44.6) | ||
| Triple therapy | 12 (21.4) | ||
PH, pulmonary hypertension; FC, functional class; BNP, B-type natriuretic peptide.
Values represent mean ± SD, unless otherwise specified.
*Available in 55 patients.
Follow-up right heart catheter data were available in 38 patients.