Table 2.
Echocardiographic measurements.
| Patients with PAH (n = 56) | |||
|---|---|---|---|
| Baseline | Follow-up | P-value | |
| Right ventricle | |||
| RV end-diastolic area, cm2 | 27 [22–32] | 23 [18–29]* | <0.001 |
| RV end-systolic area, cm2 | 20 [16–24] | 15 [12–19]* | <0.001 |
| Fractional area change, % | 25 ± 11 | 29 ± 11* | 0.010 |
| TAPSE, mm | 20 [18–22] | 21 [19–23] | 0.105 |
| PASP, mmHg | 67 ± 23† | 61 ± 21 | 0.089 |
| TAPSE/PASP, mm/mmHg | 0.29 [0.21–0.40]† | 0.35 [0.27–0.44] | 0.109 |
| RV global longitudinal strain, % | −15.1 ± 4.7 | −16.8 ± 4.8 | 0.007 |
| Tricuspid valve regurgitation | <0.001 | ||
| None/mild | 23 (41.1) | 26 (46.4) | |
| Moderate | 29 (51.8) | 21 (37.5) | |
| Severe | 4 (7.1) | 9 (16.1) | |
| Right atrium | |||
| RA area, cm2 | 17 [15–20] | 15 [12–20] | 0.014 |
| Peak longitudinal strain, % | 31 [23–36] | 29 [22–39] | 0.864 |
| Passive strain, % | 8 ± 5 | 10 ± 8* | 0.0117 |
| Peak active contraction strain, % | 21 ± 7 | 20 ± 10* | 0.704 |
| Inferior vena cava diameter, mm | 18 [15–20]† | 18 [14–21]§ | 0.928 |
PAH, pulmonary arterial hypertension; PASP, pulmonary arterial systolic pressure; RA, right atrial; RV, right ventricular; TAPSE, tricuspid annular plane systolic excursion.
Values represent mean ± SD or median (interquartile range) (for normally or non-normally distributed parameters, respectively), unless otherwise specified.
*Available in 55 patients.
Available in 52 patients.
Available in 54 patients.
§Available in 49 patients.