Fig. 1.
Contrast overview (panel A), flow diagram (B) and ROI definition (C). Panel A shows an example of a WHO grade I fibroblastic meningioma with variable consistency. Note that FA is high in the tumor periphery and central part but lower medially from the central part. That indicates that FA and MKA reflect two different aspects - MKA maps the microscopic diffusion anisotropy whereas FA shows the macroscopic diffusion anisotropy, which is lower due to low orientation coherence (Szczepankiewicz et al., 2016). Panel B shows the flow diagram of the study where the two patient populations are characterized in Table 1, respectively. The consistency analysis was performed on 16 subjects while tumor grade and tumor type analysis on 30 subjects. Panel C defines two region-of-interests (ROIs) used in the study – a “whole-tumor ROI” characterizing inner parts of the tumor and “rim ROI” characterizing the reaction in the brain tissue surrounding the tumor.