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. 2021 Nov 29;24:14–25. doi: 10.1016/j.omto.2021.11.018

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© 2021 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Combination of OAV-Decorin and CAIX-CAR-T cells improved the antitumor effect in vivo

NCG mice were subcutaneously inoculated with OSRC-2 cells (n = 5 per group). (A) Experimental timeline for in vivo studies. (B) The tumor growth curves of each individual mouse were displayed. (C) The mean tumor volume curves ±SD were displayed and the under bar graphs showed the inhibition rate of each treatment group. (D) Kaplan-Meier survival analysis of mice after different treatments. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001 (two-tailed paired t test).