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. 2021 Dec 7;8:777370. doi: 10.3389/fmolb.2021.777370

FIGURE 4.

FIGURE 4

The association between PD-1H expression levels and overall survival in ESCC. (A) The association of PD-1H mRNA expression and overall survival of patients was assessed in 41 ESCC patients and 44 EAC patients from the TCGA database. (B–D) With the applied scoring system, a score of 7.2 as the optimal cutoff point was identified by the “survMisc” package in R. The correlation between PD-1H protein expression and prolonged overall survival in 114 ESCC patients (B), in the G1 and G2/3 subgroups (C) and in the T1/T2 and T3/T4 tumor stage subgroups (D) was analyzed by using log-rank (Mantel-Cox) test in GraphPad 8.0. ESCC, esophageal squamous cell carcinoma; EAC, esophageal adenocarcinoma; G (G2/G3), Grades of differentiation; T (T1/T2, T3/T4), Tumor stage.