TABLE 1.
The correlation of PD-1H expression and clinicopathologic parameters in 114 patients with ESCC.
| N | % | PD-1H expression | ||||||
|---|---|---|---|---|---|---|---|---|
| Low | % | High | % | p-value | ||||
| Sex | Female | 32 | 28.1 | 23 | 71.8 | 9 | 28.1 | 0.811 |
| Male | 82 | 71.9 | 62 | 75.6 | 20 | 24.3 | ||
| Age group | <65 years | 85 | 74.5 | 63 | 74.1 | 22 | 25.8 | 1.000 |
| ≥65 years | 29 | 25.5 | 22 | 75.8 | 7 | 24.1 | ||
| Tumor stage | T1 | 25 | 21.9 | 15 | 60 | 10 | 40 | 0.287 |
| T2 | 21 | 18.4 | 16 | 76.2 | 5 | 23.8 | ||
| T3 | 66 | 57.8 | 52 | 78.8 | 14 | 21.2 | ||
| T4 | 2 | 1.7 | 2 | 100 | 0 | 0 | ||
| Lymph node metastasis | N0 | 51 | 44.7 | 31 | 60.8 | 20 | 39.2 | 0.020 |
| N1 | 35 | 30.7 | 30 | 85.7 | 5 | 24.3 | ||
| N2 | 23 | 20.1 | 19 | 82.7 | 4 | 17.3 | ||
| N3 | 5 | 4.3 | 5 | 100 | 0 | 0 | ||
| Grades of differentiation | G1 | 38 | 33.3 | 25 | 65.8 | 13 | 34.2 | 0.276 |
| G2 | 55 | 48.2 | 43 | 78.2 | 12 | 21.8 | ||
| G3 | 9 | 7.8 | 8 | 88.8 | 1 | 11.2 | ||
| UICC stage | I | 27 | 23.7 | 17 | 63 | 10 | 37 | 0.009 |
| II | 37 | 32.4 | 23 | 62.2 | 14 | 37.8 | ||
| III | 44 | 38.6 | 39 | 88.6 | 5 | 11.4 | ||
| IV | 6 | 5.3 | 6 | 100 | 0 | 0 | ||
UICC, union for international cancer control; PD-1H, Programmed death-1 homolog; ESCC, esophageal squamous cell carcinoma.