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. 2021 Dec 7;9:762489. doi: 10.3389/fbioe.2021.762489

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Copyright © 2021 Wang, Zhou, Xu, Peng, Zhang, Li, Zhang, Zhang, Cheng, Wang, Wei, Yue, Yang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TPGS-Res-SLNs inhibited invasion and migration ability of SKBR3/PR cells in vitro (A) Transwell migration assay was used to detect the number of trans-membrane cells. Representative microphotographs of the Boyden chamber assay of SKBR3/PR cells. (B) The quantitative data for the Boyden chamber assay. The bar graph represents the number of invasive cells present per unit area in different treated groups. (C) Wound-healing assays were performed to assess cell migration. Cells were treated with Resveratrol, Res-SLNs and TPGS-Res-SLNs for 0 and 24 h or untreated. Representative images of treated and untreated cells are shown. (D) Distance migrated by cells at the 24 h are shown. The values represent the mean ± SD of three independent experiments. (**p < 0.01, *p < 0.05).