TABLE 3.
Proteases and protease inhibitors significantly elevated in Sjogren’s Syndrome (SS) saliva over healthy controls.
| Uniprot ID | Gene name | Protein name | Fold difference SS/healthy |
|---|---|---|---|
| Elevated in Sjogren’s Syndrome | |||
| Q99497 | PARK7 | DJ-1/Parkinson disease protein 7 | 3.9 |
| P08311 | CTSG | Cathepsin G | 3.8 |
| P08246 | ELANE | Neutrophil elastase | 3.6 |
| P02788 | LTF | Lactransferrin | 3.6 |
| P20160 | AZU1 | Azurocidin | 3.3 |
| P09228 | CST2 | Cystatin-SA | 3.1 |
| P20810 | CAST | Calpastatin | 3.1 |
| P24158 | PRTN3 | Proteinase 3/Myeloblastin | 3.0 |
| P01009 | SERPINA1 | Alpha-1-antitrypsin | 2.9 |
| O60235 | TMPRSS11D | Transmembrane protease serine 11D | 2.5 |
| Elevated in healthy | |||
| P16870 | CPE | Carboxypeptidase We | -4.0 |
| Q9HC84 | MUC5B | Mucin-5B | −3.4 |
| P01037 | CST1 | Cystatin-SN | −3.2 |
| P28325 | CST5 | Cystatin-D | −2.8 |
| P01036 | CST4 | Cystatin-S | −2.6 |
| P22894 | MMP8 | Neutrophil collagenase | −2.5 |
| P29508 | SERPINB3 | Serpin B3 | −2.5 |
| P03973 | SLPI | Antileukoproteinase | −2.0 |