Dunn 2019.
Study characteristics | ||
General information | Objective
Journal
Country
Study design
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Participants | Number of included patients
Surgical specialty
Age
Male sex
High‐risk surgery
Insulin‐dependent diabetes mellitus
History of ischaemic heart disease
History of congestive heart failure
History of cerebrovascular events
Elevated creatinine
0 RCRI factors
1 RCRI factor
2 RCRI factors
3 or more RCRI factors
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Predictors | Predictor 1: ASC‐NSQIP‐MICA
Predictor 2: PORT model
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Outcome | Outcome category
Full outcome definition
Prediction horizon
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Analysis | Number of outcomes
Handling missing data
Discrimination reported?
Calibration reported?
Reclassification reported?
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PROBAST: Applicability | Domain 1: Participant selection
Justification: only kidney transplants Domain 2: Predictors
Justification: definition of ischaemic heart disease is different from the definition in the development study and no information on blinding Domain 3: Outcome
Justification: outcome is myocardial infarction and cardiac arrest, which is different from the definition from the development study Overall judgement
Justification: only a selected group of patients was included; predictor definitions were different from the predictor definitions used in the development study. In addition, outcome definition was different compared to the development study. |
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Notes | — | |
Item | Authors' judgement | Support for judgement |
Domain 1: Participant selection | Yes | Although only patients undergoing kidney transplant surgery were included, participant selection was appropriate and the RCRI model can be applied in these patients. |
Domain 2: Predictors | No | Definition of ischaemic heart disease is different from the definition in the development study and no information on blinding. |
Domain 3: Outcome | Unclear | No information on how myocardial infarction is defined/diagnosed. |
Domain 4: Analysis | No | Low number of outcomes; complete case analyses; c‐statistic was not provided for the RCRI alone; no information on calibration and reclassification. |
Overall judgement | No | Patient selection was appropriate. However, predictors were defined differently compared to predictor definitions used in the development study. In addition, the number of outcomes was low, complete case analysis was performed and no calibration and reclassification was reported. |