Table 1.
The distribution of TSH concentrations (mU/l) in the total sample and based in age, sex and TPO, Tg antibodies groups.
| 2006 | 2011 | ||||||||||||||
| Percentile | Percentile | ||||||||||||||
|
Mean± SD
[Min-Max] |
5th | 95th | 2.5th | 97.5th | P |
Mean± SD
[Min-Max] |
5th | 95th | 2.5th | 97.5th | P | ||||
| Total sample (n=1899) | 2.0±1.19 [0.2-9.9] |
0.6 | 3.9 | 0.4 | 4.95 | p<0.001* |
Total sample
(n=377) |
2.11±1.11 [0.4-7.8] |
0.7 | 4.3 | 0.7 | 4.9 | 0.002* | ||
| Sex |
Female
(n=788) |
2.19±1.23 [0.3-9.9] |
0.6 | 4.4 | 0.5 | 5.3 |
Female
(n=142) |
2.41±1.16 [0.4-6.6] |
1.0 | 4.7 | 0.77 | 5.55 | |||
|
Male
(n=1111) |
1.87±1.15 [0.2-9.7] |
0.5 | 3.7 | 0.4 | 4.72 |
Male
(n=235) |
2.07±1.26 [0.14-9.8] |
0.7 | 4.64 | 0.6 | 5.7 | ||||
| Age |
≤30
(n=549) |
1.97±1.12 [0.3-7.5] |
0.6 | 3.9 | 0.47 | 4.8 | 0.83** |
≤30
(n=34) |
2.13±0.94 [0.5-4.9] |
0.7 | 3.59 | 0.5 | 4.86 | 0.35** | |
|
31-40
(n=457) |
1.98±1.13 [0.2-9.7] |
0.5 | 3.9 | 0.4 | 4.5 |
31-40
(n=65) |
2.0±1.02 [0.4-4.7] |
0.64 | 4.61 | 0.4 | 6.25 | ||||
|
41-50
(n=511) |
2.0±1.15 [0.3-9.9] |
0.7 | 4.0 | 0.5 | 5.12 |
41-50
(n=94) |
1.99±1.05 [0.5-6.6] |
0.81 | 4.66 | 0.7 | 6.09 | ||||
|
≥50
(n=382) |
2.04±1.4 [0.3-9.5] |
0.6 | 4.78 | 0.4 | 6.67 |
≥50
(n=182) |
2.21±1.19 [0.5-7.8] |
0.73 | 4.87 | 0.66 | 5.57 | ||||
| TPO |
Positive
(n=134) |
4.9±2.42 [0.2-9.4] |
0.47 | 9.07 | 0.2 | 9.4 | 0.000* |
Positive
(n=98) |
2.49±1.41 [0.14-6.8] |
0.04 | 7.08 | 0.02 | 14.62 | 0.006** | |
|
Negative
(n=325) |
3.36±2.18 [0.2-9.7] |
0.3 | 7.22 | 0.22 | 8.28 |
Negative
(n=336) |
2.12±1.13 [0.4-7.8] |
0.7 | 4.7 | 0.53 | 6.3 | ||||
| Tg |
Positive
(n=135) |
4.34±2.43 [0.2-8.8] |
0.24 | 8.64 | 0.2 | 8.80 | 0.09* |
Positive
(n=5) |
4.76±3.53 [1.1-9.8] |
1.1 | 24.0 | 1.1 | 24.0 | 0.002* | |
|
Negative
(n=324) |
3.53±2.27 [0.2-9.7] |
0.35 | 7.63 | 0.22 | 8.64 |
Negative
(n=32) |
2.08±1.15 [0.5-4.9] |
0.05 | 4.3 | 0.02 | 4.9 | ||||
*result from independent t-test or Mann-Whitney U test, ** result from ANOVA or Kruskal-Wallis