Table 1.

Comparison of Demographic and Biochemical Characteristics between Groups

Quantitative variables Mean ± SD	Group 1 (Normal Prolactin) (N=208)	Group 2 (Macroprolactin) (N=72)	Group 3 (Pituitary Adenoma) (N=33)	Group 4 (Idiopathic Hyperprolactinemia) (N=17)	P-value
Age(year)	25.51±13.25	23.49±4.91	24.94±3.71	24.24±3.23	0.6
BMI(Kg/m2)	25.36±3.82	24.25±6.21	30.59±31.40	28.60±17.70	0.1
FBS(mmol)	4.86±0.69	4.84±0.62	4.86±0.83	4.76±0.97	0.9
Insulin level mlU/ml	12.19±5.17	11.58±3.69	11.03±4.85	10.77±2.39	0.3
HOMA-IR	2.67±1.20	2.54±0.88	2.53±1.23	2.29±0.75	0.3
LH mlU/ml	8.63±3.74	7.02±3.35	7.49±3.54	7.01±3.79	0.01§
FSH mlU/ml	5.39±1.97	5.55±2	6.18±2.03	4.77±1.92	0.09
LH/FSH	1.82±1.51	1.39±0.77	1.37±1.43	1.29±0.69	0.02§
T-testosterone ng/ml	0.86±1.50	0.84±1.11	0.64±0.15	0.58±0.18	0.6
Prolactin ng/ml	16.93±4.81	41.56±4.61	59.19±8.56	44.56±8.85	0.001§
TSH mlU/ml	3.92±11.46	4.56±12.73	2.23±0.95	2.25±0.95	0.7
Estradiol pg/ml	38.84±30.60	43.73±21.04	49.06±19.31	50±57.3	0.01,0.04ᶲ

^§Group 1 Vs. Group 2, 3, 4; ᶲ Group 1 Vs. Group 2, 3 (P=0.01), Group 1 Vs. Group 4 (P=0.04)