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. 2021 Dec 20;4(12):e2137250. doi: 10.1001/jamanetworkopen.2021.37250

Table 1. Demographic Characteristics of Case and Control Parents by Cohort.

Characteristics Parents, No. (%) P value
Case cohort Control cohort
Prematurity cohort
Parents, No. 2093 6062 NA
Age, y
<19 2 (0.1) 0 .001
19 to <29 204 (9.8) 667 (11.0)
29 to <39 1407 (67.3) 4178 (68.9)
39 to <49 435 (20.8) 1140 (18.8)
≥49 44 (2.1) 77 (1.3)
Sex
Female 1158 (55.3) 3151 (52.0) .009
Male 935 (44.7) 2911 (48.0)
Race and ethnicity
Asian 115 (5.5) 391 (6.5) <.001
Black 243 (11.6) 397 (6.6)
Hispanic 248 (11.9) 564 (9.3)
White 1345 (64.3) 4269 (70.4)
Missing or other 142 (6.8) 441 (7.3)
Cardiac cohort
Parents, No. 1610 4773
Age, y
<19 2 (0.1) 0 .01
19 to <29 165 (10.3) 535 (11.2)
29 to <39 1072 (66.6) 3266 (68.6)
39 to <49 339 (21.1) 907 (19.0)
≥49 31 (1.9) 65 (1.4)
Sex
Female 860 (53.5) 2943 (52.3) .41
Male 749 (46.6) 2279 (47.8)
Race and ethnicity
Asian 98 (6.1) 307 (6.4) .005
Black 153 (9.5) 325 (6.8)
Hispanic 152 (9.5) 421 (8.8)
White 1109 (68.9) 3386 (70.9)
Missing or other 98 (6.1) 334 (7.0)
Oncologic cohort
Parents, No. 2655 6502 NA
Age, y
<19 10 (0.4) 0 <.001
19 to <29 30 (1.1) 114 (1.8)
29 to <39 698 (26.3) 1513 (23.3)
39 to <49 1297 (48.9) 3154 (48.5)
≥49 620 (23.4) 1721 (26.5)
Sex
Female 1344 (50.6) 3295 (50.7) .96
Male 1311 (49.4) 3207 (49.3)
Race and ethnicity
Asian 159 (6.0) 381 (5.9) .12
Black 114 (4.3) 363 (5.6)
Hispanic 279 (10.4) 667 (10.3)
White 1969 (74.1) 4781 (73.5)
Missing or other 138 (5.2) 310 (4.8)
Neurologic cohort
Parents, No. 5679 14 434 NA
Age, y
<19 12 (0.2) 1 (0.01) <.001
19 to <29 114 (2.0) 390 (2.7)
29 to <39 1574 (27.7) 3910 (27.1)
39 to <49 2651 (46.7) 6590 (45.7)
≥49 1328 (23.4) 3543 (24.6)
Sex
Female 2879 (50.7) 7375 (51.1) .61
Male 2800 (49.3) 7059 (48.9)
Race and ethnicity
Asian 293 (5.2) 919 (6.4) <.001
Black 316 (5.6) 863 (6.0)
Hispanic 659 (11.6) 1466 (10.2)
White 4139 (72.9) 10 580 (73.3)
Missing or other 273 (4.8) 606 (4.2)

Abbreviation: NA, not applicable.