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. 2002 Oct 21;2002(4):CD002992. doi: 10.1002/14651858.CD002992

Chodosh 1988.

Methods Single‐dose 
 Cross‐over 
 Double‐blind 
 Dropout: 11% prior to study beginning
Participants n = 16 
 Mean age = 39 
 Inclusion: normotensive patients with stable bronchial asthma, > 15% increase FEV1 and FEV1 60% to 90% predicted 
 Exclusion: taking cromolyn, their steroid or inhaler use changed, recent asthma attack requiring Tx , upper respiratory infection within 2 weeks or recent status asthmaticus
Interventions #1: 
 Metoprolol 200 mg 
 Placebo 
 #2: 
 Inhaled isoproterenol after Tx and placebo
Outcomes FEV1 
 Symptoms
Notes Nonselective studied: dilevalol