Figure 2.
Correlation of antibody levels and magnitude of antigen-specific T-cell response in solid organ transplant recipients (SOTRs). Proportions of spike-specific interferon gamma (IFN-γ) monofunctional (A), interleukin 2 (IL-2) monofunctional (B), or IFN-γ and IL-2 polyfunctional (C) CD4+ T cells relative to levels of anti-spike receptor-binding domain (RBD) antibodies (U/mL). Similar plots are shown for nucleoprotein (NP)–specific IFN-γ monofunctional (D), IL-2 monofunctional (E), or IFN-γ and IL-2 polyfunctional (F) CD4+ T cells relative to levels of anti-NP antibody level (U/mL). Each dot corresponds to 1 participating SOTR. Spearman r for each comparison is shown in the top right of each plot, along with the corresponding P value.