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. 2020 Oct 16;42(6):474–487. doi: 10.1027/0227-5910/a000753

Table A1. Characteristics of included publications.

Study, country, and study period Population Public Health Emergency Suicide/Self-harm Main findings Quality assessment
Sample/Source Sex/Age Exposure/Measures Main public health responses Outcomes/Measures
Huang et al. (2005) [Taiwan] Study period: 2003 Emergency department adult patients in a SARS-dedicated hospital. Adults > 14 years Exposure: Severe Acute Respiratory Syndrome (SARS). Measures: Not reported. Not reported. Attempted suicide via medication self-poisoning. Measures: Emergency Department Medical Records. Increase in suicide attempts by self-poisoning during peak epidemic stage; not statistically significant. 3
Wasserman (1992) [USA] Study period: 1910–1920 USA citizens. Source: The US Bureau of the Census (1910–1920). Not reported. Exposure: The Great Influenza Epidemic//"Spanish Flu." Measures: Spanish Flu: Mortality data from the US Bureau of the Census (1922). Social distancing (closure of schools, churches, theaters, moving picture halls, dance halls, saloons, and sporting arenas, curtailment of the 1918 political campaign. Some states were forced to don gauze masks). Outcome: Suicide deaths. Measures: Surveillance data. Mortality rate during the Spanish Flu (1918–1920) was positively associated with an increase in suicide rates. 5
Honigsbaum (2010) [UK] Study period: 1889–1893 UK citizens (with a focus on Sheffield and other northern towns). Not reported. Exposure: Russian influenza. Measure: Historical archives (medical officer of health and national and local newspaper reports, and the poetry and memoirs of prominent survivors). Not reported. Outcome: Suicide deaths. Measures: Surveillance data, historical documents. The epidemic coincided with a marked rise in the suicide rate. Coroners' verdicts of suicide in England and Wales, of whom 60% were male, increased by 25% between 1889 and 1893, and in 1893 the suicide rate peaked at 8.5/100,000, "the highest on record." 5
Yip et al. (2010) [Hong Kong] Study period: 2003 Older adults in Hong Kong aged > 65 who died by suicide that was SARS-related. N = 22. Source: Coroner Court reports. Sex: M = 11, F = 11. Mean age: 74.9 (≥ 65), general population. Exposure: Severe Acute Respiratory Syndrome (SARS). Measure: Number of deaths from confirmed affected individuals. Quarantine actions at several hospitals and hotspots to control the spread of the disease. In addition, social contact and networking within the community was reduced to minimize the epidemic's spread. Outcome: Suicide deaths that were SARS-related. Measures: Suicide notes and witnesses' descriptions of the suicide deaths. SARS-related older-adult suicide dead were more likely to be afraid of contracting the disease (χ2 = 29.33, df = 1, p < .001) and had fears of disconnection (χ2 = 9.26, df = 1, p < .002). The SARS-related suicide dead feared being a burden to their families during the epidemic. No significant differences in sociodemographics, employment status, medical or psychiatric profiles, and level of dependence on others. 4
Keita et al. (2017) [Guinea, West Africa]Study period: 23/03/15–11/07/16. N = 256 for total study. n = 33 for clinical observation with a psychiatrist. Individuals aged ≥ 20, participating in the PostEboGui study, who were receiving care at the Conakry site, and who had completed the CES-D. Sex: M = 118; F = 138. Age median: 32 (26–41). Exposure: Ebola virus disease (EVD). Measure: Having EVD confirmed by laboratory exams and being admitted to the Ebola Treatment Center for treatment. Not reported. Outcomes: Suicidal ideation and suicide attempt. Measures: Clinical interview with a psychiatrist. Thirty-eight participants (15%) had a score higher than the threshold value of the CES-D for depressive symptoms. In 33 participants who had a clinical consultation with a psychiatrist following completion of the CES-D, 1 person presented with suicidal ideation and 3 participants had attempted suicide. 3
Chan et al. (2006) [Hong Kong] Study period: 1986–2003. All individuals aged ≥ 65 who died by suicide in Hong Kong during 1986–2003. Source: Census & Statistics Department of the Government of Hong Kong Special Administrative Region. Sex: Not reported. Age: ≥ 65. Exposure: Severe Acute Respiratory Syndrome (SARS). Measure: Number of deaths from confirmed affected individuals. Resources were channeled to combating SARS at the expense of routine nonemergency healthcare services. Widespread disruptions in social networking were evident as most residents in Hong Kong minimized their outings. Outcome: Suicide deaths. Measures: Surveillance data. There was a significant rise in older adult suicide rates from 2002 to 2003 (IRR = 1.32, p = .002). This increase reached statistical significance for women (IRR = 1.42; p = .014) but not for men (IRR = 1.22; p = .087) or those under 65 (IRR = 0.97; p = .48). 5
Cheung et al. (2008) [Hong Kong] Study period: 1993–2004. All individuals ≥ 65 years of age who died by suicide in Hong Kong during 1993–2004. N = 321 (detailed information obtained for n = 303). Source: Hong Kong Coroners' Court. Sex: M = 181; F = 122. Age: ≥ 65. Exposure: Severe Acute Respiratory Syndrome (SARS). Measure: Number of deaths from confirmed affected individuals. Due to the fear of contracting SARS, older adults reduced social contacts and were housebound voluntarily and/or involuntarily. Besides, the quarantine measures imposed to curtail the spread of the epidemic also played a role in weakening social networks. Outcome: Suicide deaths. Measures: Surveillance data. Results showed an excess of older adult suicides in April 2003, when compared with April of previous years. The annual older-adult suicide rates in 2003 and 2004 were significantly higher than that in 2002, suggesting the suicide rate did not return to the level before the SARS epidemic. Overall severity of illness (χ2 = 25.104, df = 6, p < .001), level of dependency (χ2 = 12.697, df = 6, p < .013), and worrying about having sickness (χ2 = 7.721, df = 2, p < .021) among the older adult suicides were found to be significantly different in the pre-, peri-, and post-SARS periods. 6
Okusaga et al. (2011) [USA] Study period: not provided. Clinical sample of mood disorder patients versus healthy controls. Sex (depressed sample): M = 95; F = 162. Mean age: 43.4 (SD = 10.9). Seropositivity for coronaviruses, influenza A and B viruses; not related to particular epidemic exposure. Not applicable. Columbia Suicide History Form Interview Among individuals with a history of mood disorder, seropositivity for influenza B was significantly associated with a history of suicide attempt(s), 96 (97.0%) versus 104 (83.9%; p = .001), and the odds of having attempted suicide were increased in influenza B seropositive individuals (OR = 2.53, 95% CI [1.33, 4.80]). No association with influence A or coronaviruses. 1