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. 2021 Nov 12;50(D1):D687–D692. doi: 10.1093/nar/gkab1028

Figure 3.

Figure 3.

The IDG portal incorporates new features to help users visualize potential functions of understudied (‘dark’) proteins in the context of Reactome pathways. The screenshot shows some of these features, including level of knowledge of each displayed protein as a drug target (i.e. Tclin, target of drugs with known mechanism of action, Tchem, target of drugs (no mechanism), Tbio, well-characterized protein not known to be targeted by any drug, Tdark, poorly characterized protein not known to be targeted by any drug, http://juniper.health.unm.edu/tcrd/, overlaying pairwise relationships from different resources (e.g. BioGrid, BioPlex and StringDB), and a new network view.