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. 2021 Nov 29;50(D1):D460–D470. doi: 10.1093/nar/gkab1080

Table 2.

Comparison of the data statistics from this update and the previous version in terms of functional activities

Function classes Against activity dbAMP dbAMP 2.0a (%)
Antibacterial Antibacterial 3006 4837 (18.29)
Anti-Gram-positive 2726 11 652 (44.06)
Anti-Gram-negative 2323 12 405 (46.91)
Antimicrobial 4816 8654 (32.72)
Antibiofilm 40 40 (0.14)
Mollicute 36 (0.14)
Antiyeast 4 5 (0.02)
Antilisterial 2 (0.01)
Antifungal Antifungal 1623 5454 (20.62)
Antiviral Antiviral 300 1745 (6.60)
Anti-SARS/CoV 186 (0.70)
Antiparasitic Antiparasitic 123 186 (0.70)
New function peptides Mammalian cells 308 402 (1.52)
Anuran defense 7256 (27.44)
Insecticidal 35 1791 (6.77)
Antiprotozoal 6 195 (0.74)
Chemotactic 59 61 (0.23)
Antimalarial 26 46 (0.17)
Antinematode 46 (0.17)
Antiplasmodial 35 (0.13)
Cell penetrating 29 (0.11)
Enzyme inhibitor 26 26 (0.10)
Wound healing 19 21 (0.07)
Antibiotic 19 (0.07)
Immunomodulant 17 (0.06)
Spermicidal 13 13 (0.05)
Edema inducer 11 (0.04)
Disease-associated peptides Anticancer 227 2290 (7.98)
Anti-HIV 109 2286 (8.64)
Antitumor 9 1018 (3.85)
Anti-HCV 67 (0.25)
Antiangiogenesis 13 (0.05)
Anti-HSV 10 (0.04)
Antiallodynic 1 (0.01)
New mechanism-associated peptides Antihypertensive 1 (0.01)
Anti-MRSA 874 (3.30)
Antidiabetic 113 (0.43)
Antioxidant 22 31 (0.12)
Surface immobilized 19 27 (0.10)
Mast cell degranulating 18 (0.07)
Uterotonic 6 (0.02)
Anti-inflammatory 6 (0.02)
Antineurotensive 4 (0.02)
Plasma anticlotting 3 (0.01)
Proteolytic 2 (0.01)
Antinociceptive 2 (0.01)
Hypotensive 1 (0.01)
Sodium channel blocker 2 2 (0.01)
Toxic Cytotoxin 1 (0.01)
Hemolytica 115 (0.43)
Cytolytic 98 (0.37)
Ichthyotoxic 14 (0.05)
a

The numbers in parentheses are displayed as theproportion of entries in the dbAMP.