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. 2001 Apr;21(8):2755–2766. doi: 10.1128/MCB.21.8.2755-2766.2001

TABLE 1.

Caffeine does not mediate premature DNA condensation in cells with Cdk2-dn inductiona

Transfection Condensed nuclei (%)b
+Tet −Tet
No caffeine 5.3 ± 0.9 3.2 ± 2.6
Caffeine 20 ± 2.0 5.1 ± 2.4
a

Cells were synchronized with HU, released for 4 h, incubated with 1 mM caffeine for another 8 h, fixed, and stained with bisbenzimide (Hoechst). 

b

Mean ± standard deviation from three independent experiments.