Figure 5.

In vivo PTT of IR780@SAC4A. (A) Thermal images of 4T1 tumor-bearing mice received intravenous injection of free IR780 or IR780@SAC4A upon irradiation with 808 nm laser at different time (1.0 W cm^-2). (B) Changes in temperature of tumors upon 808 nm laser irradiation. (C) Tumor volume growth curves of mice treated with different interventions. (D) Images of dissected tumors in various groups. White circles indicate the eliminated tumors. (E) Weights of tumors dissected from mice in different groups after 21 days of treatment. (F) H&E staining of tumor slices after different treatments. Scale bar, 50 μm. The data are shown as mean ± SD (n = 5). P values were calculated by Student's t test: ***P < 0.001.