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. 2022 Jan 1;12(1):434–458. doi: 10.7150/thno.67300

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Schematic illustration of emerging nanomedicines for PDT-driven cancer immunotherapy. The outer shell shows recent nanomedicines developed for PDT-driven cancer immunotherapy, including tumor hypoxia-reversed nanomedicines, UCNs, nanosized nMOFs, TME-responsive NPs, subcellular targeted NPs, carrier-free and small-molecule prodrug-based self-assembled NPs, and multifactor-driven nanomedicines. The inner core explains how to amplify the combination of PDT and immunotherapy, thereby improving the effect of cancer treatment.