Table 1.
Clinical parameters of patients' samples and sequenced map reads output used in this study.
| No IM | Low Risk IM | High Risk IM | Dysplasia | P values | |
|---|---|---|---|---|---|
| N = 43 | 17 | 16 | 6 | 4 | - |
| Age (mean (SD)) | 54.82 (5.00) | 62.25 (7.49) | 64.33 (10.84) | 59.75 (5.74) | 0.011 |
| Sex = Male (%) | 6 (35.3) | 12 (75.0) | 5 (83.3) | 3 (75.0) | 0.055 |
| Clinical history of H. pylori infection = Yes (%) | 14 (82.4) | 9 (56.2) | 4 (66.7) | 4 (100.0) | 0.21 |
| IM grade (%) | < 0.001 | ||||
| Negative | 17 (100.0) | 0 (0.0) | 0 (0.0) | 2 (50.0) | - |
| Mild | 0 (0.0) | 3 (18.8) | 0 (0.0) | 0 (0.0) | - |
| Moderate | 0 (0.0) | 6 (37.5) | 1 (16.7) | 0 (0.0) | - |
| Marked | 0 (0.0) | 7 (43.8) | 5 (83.3) | 2 (50.0) | - |
| Multi focal IM (%) | 0 (NaN) | 2 (12.5) | 6 (100.0) | 2 (100.0) | NaN |
| Transition (%) | < 0.001 | ||||
| Baseline dysplasia | 0 (0.0) | 0 (0.0) | 0 (0.0) | 4 (100.0) | - |
| Developed EGN | 1 (5.9) | 7 (43.8) | 5 (83.3) | 0 (0.0) | - |
| No subsequent EGN | 16 (94.1) | 9 (56.2) | 1 (16.7) | 0 (0.0) | - |
| Map reads (mean (SD)) | 24246.41 (26665.40) | 17889.25 (13308.57) | 20217.00 (18521.55) | 20051.75 (19164.68) | 0.852 |