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. Author manuscript; available in PMC: 2021 Dec 21.
Published in final edited form as: Anticancer Res. 2021 Dec;41(12):5919–5933. doi: 10.21873/anticanres.15411

Figure 1.

Figure 1.

The effect of DATS on viability oϕ MDA-MB-231 (A) and MDA-MB-468 (B) TNBC cells. MDA-MB-231 and MDA-MB-468 were treated with various concentrations (0-200 μM) of DATS for 24, 48, and 72 h. The effect of DATS was both dose- and -time-dependent. Treatment with a low dose of 25 μM of DATS significantly decreased cell viability compared to control. DMSO treatment showed no cytotoxicity at any time point. The lethal concentration 50 (LC50) value was acquired from GraphPad Prism using mean values of data points at the previously mentioned concentrations. All experiments were performed at least three times with n=3. The data are presented as the mean±SEM. Statistically significant differences between control vs. treatments were evaluated by a one-way ANOVA, followed by’ ‘Dunnett’s multiple comparison test or Student’s t-test to compare the results between the two cell lines with ***p<0.001.