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. Author manuscript; available in PMC: 2021 Dec 21.
Published in final edited form as: Pediatrics. 2011 Jan;127(1):e252–e254. doi: 10.1542/peds.2010-3381A

TABLE 1.

Location of Pediatric Subjects in Clinical Trials 2002–2007

Patient No.
(%)
Cardiovascular trials (N = 1539)a
 Developed countriesb
  United States 798 (51)
  Netherlands 398 (26)
  Canada 61 (4)
  Hungary 36 (2)
  Norway 35 (2)
  New Zealand 16 (1)
 Developing/transition countriesb
  South Africa 53 (3)
  Argentina 22 (1)
  Chile 20 (1)
  Russia 20 (1)
  Brazil 16 (1)
  Peru 11 (1)
Juvenile rheumatoid arthritis trials (N = 556)
 Developed countriesb
  United States 180 (32)
  Israel 52 (9)
  Germany 42 (8)
  Australia 42 (8)
  Norway 30 (5)
  Austria 22 (4)
  Portugal 21 (4)
  Italy 9 (2)
 Developing/transition countriesb
  Peru 47 (8)
  Argentina 42 (8)
  Brazil 40 (7)
  Mexico 21 (4)
  Chile 8 (1)
a

Cardiovascular conditions studied included hypertension, heart failure, arrhythmia, and heterozygous familial hypercholesterolemia.

b

This delineation is subjective and based on a United Nations reference that indicates that the delineation is not an established convention and should be viewed as a generalization.