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. 2021 Dec 21;2021(12):CD002008. doi: 10.1002/14651858.CD002008.pub5

Hebuterne 2019.

Methods Multicentre RCT.
Participants 173 participants with metastatic colorectal cancer receiving chemotherapy.
Interventions Early & active individualised dietary counselling by a dietitian with ONS and enteral & parenteral feeding prescribed according to guidelines versus no dietary counselling.
Outcomes Primary outcome: grade >3 toxicity.
Secondary outcomes: treatment delay, weight.
Notes Currently available as an abstract only.  Full details of the intervention needed as well as numbers of participants going on to receive EN and PN needed to judge eligibility.