Figure 1.

Reward Deficiency Syndrome Solution^TM for identification of risk alleles with the Genetic Addiction Risk Severity (GARS). The figure describes the Reward Deficiency Syndrome Solution System^TM that proposes using the Genetic Addiction Risk Severity (GARS) to identify and stratify risk alleles for targeting by individualized nutrigenomic preparations. Our approach called “Precision Behavioral Management” consists of; 1) Early pre-disposition assessment and determination (even in children) with the Genetic Addiction Risk Severity (GARS), a 10 candidate polymorphic gene panel shown to predict ASI-alcohol and drug severity; 2) validated RDS questionnaire; 3) Utilization of the Comprehensive Analysis of Reported Drugs (CARD™) during actual treatment to determine compliance with prescribed medications and abstinence from non-prescribed and illicit drugs of abuse, and importantly; 4) Utilization of a “Pro-Dopamine Regulator (KB220)” (via IV and oral [KB220Z] delivery systems) to prevent relapse by induction of dopamine homeostasis, and; 5) Utilization of targeted DNA polymorphic reward genes to direct mRNA genetic expression profiling during the treatment process.