Table 1. Affinity of the Aptamers for S1 and RBD SARS-CoV-2 S Protein Domains.
S1 |
RBD |
|||
---|---|---|---|---|
KD (nM) | R2 | KD (nM) | R2 | |
Apt1 | 10.2 ± 2.7 | 0.9875 | 39.0 ± 11.2 | 0.9903 |
Apt2 | 0.2 ± 0.1 | 0.9768 | 7.7 ± 1.4 | 0.9887 |
Apt3 | 5.3 ± 0.5 | 0.9976 | 10.9 ± 2.9 | 0.9706 |
Apt4 | 3.3 ± 0.7 | 0.9869 | 34.6 ± 17.8 | 0.9851 |
Apt5 | 11.3 ± 6.1 | 0.9810 | 29.8 ± 17.8 | 0.9713 |
Apt6 | 3.4 ± 1.1 | 0.9879 | 32.2 ± 7.3 | 0.9701 |
Apt1C | 8.1 ± 1.0 | 0.9939 | 21.0 ± 2.7 | 0.9916 |
Apt4C | 11.1 ± 2.7 | 0.9623 | 20.8 ± 5.4 | 0.9792 |