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. 2021 Nov 23;42(1):49–62. doi: 10.1161/ATVBAHA.121.317113

Figure 3.

Figure 3.

Abundance of S100A8 and S100A9 in platelets depends on neutrophils. A, S100A8/A9 is commonly considered to be of neutrophil origin. In patients with stable coronary artery disease (blue), plasma S100A8/A9 positively correlates with neutrophil count. However, this association is less strong in individuals experiencing ST-segment–elevation myocardial infarction (STEMI; red). B, When analyzed by time point, the association of plasma S100A8/A9 with neutrophil count is seen primarily at day 3 after STEMI or coronary artery bypass grafting (CABG). C, Platelet levels of S100A8 and (D) S100A9 were strongly positively correlated with neutrophil count at the time of STEMI, but no correlation was seen at day 3 for either protein.