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Effect of DOPET treatment on protein expression of apoptotic markers. LPS-intoxicated rats showed significant (p < 0.05) upregulation of Bax, caspase-3, and downregulation of Bcl-2 and treatment with DOPET markedly restored the expression to normal (a). Relative mRNA expression of apoptotic markers (b). Data are depicted as mean ± SEM (n = 3). (a) LPS vs control; (b) LPS + DOPET vs LPS. * Significant (p < 0.05).
